Steelers play it safe with Clark

B0007446 Sickle-cell anaemia


B0007446 Sickle-cell anaemia
Credit: 'EM Unit, UCL Medical School, Royal Free Campus'. Wellcome Images
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Normal red blood cell (background, coloured red) and red blood cell affected by sickle-cell anaemia (foreground, coloured red).

Sickle-cell anaemia is a blood disease that causes the cell to form a characteristic sickle-shape. This change in shape affects the cell\'s ability to carry haemoglobin (an iron-rich protein that gives red blood cells their colour and allows for efficient oxygen transport)..
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Sickle-cell anaemia results in abnormal blood flow and a reduction in the red blood cell count. It is a genetic disorder that results when an individual has two copies of the relevant gene. It is common in countries in which malaria is prevalent, as carrying one copy of the sickle-cell gene provides advantageous resistance to malaria and is known as \'sickle-cell trait\'.

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Scanning electron micrograph
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sickle cell trait Video

Sickle cell anemia is a disease that is passed down within families that results in abnormally shaped red blood cells. Red blood cells work to deliver oxygen to all parts of the body. When these red blood cells are fragile and misshapen as they are in sickle cell anemia, the body cannot get adequate oxygen. The disease occurs when a person has inherited the sickle cell trait from both parents. A child with the disease will have painful symptoms and will most likely be physically unable to participate in athletics. However, a child who has inherited the sickle cell trait from only one parent does not have the disease and may not have any symptoms at all. They may be totally unaware that they have this trait, but they may be at greater risk of complications while playing sports.
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sickle cell trait Video

The NCAA recommends that athletics departments confirm the sickle cell trait status in all student-athletes.
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